I like to cut the mids on my amplifier EQ ( 5150 II --- mids at 1, bass at ten, Treble at 6-7 ) and use my EQ pedal to give me just enough mid to cut through the mix when I'm playing with others. This amplifier articulates this sound particularly well.

Don't worry about being associated with the Line 6 users who play Trapt and scoop the mids by scooping your own ... if you can play then you won't have that problem.